منابع مشابه
Funding and Innovation in Diseases of Neglected Populations: The Paradox of Cryptococcal Meningitis.
It is estimated that fungal infections cause 1 million deaths annually, accounting for 50% of all AIDS-related deaths [1]. In this specific patient group, data from 2009 revealed that fungal meningitis is responsible for approximately 500,000 deaths each year [2]. The most common fungal pathogen infecting the brain is Cryptococcus neoformans, a yeastlike pathogen that is highly efficient in cau...
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The current drug R&D pipeline for most neglected diseases remains weak, and unlikely to support registration of novel drug classes that meet desired target product profiles in the short term. This calls for sustained investment as well as greater emphasis in the risky upstream drug discovery. Access to technologies, resources, and strong management as well as clear compound progression criteria...
متن کاملEthical issues in funding research and development of drugs for neglected tropical diseases.
Neglected and tropical diseases, pervasive in developing countries, are important contributors to global health inequalities. They remain largely untreated due to lack of effective and affordable treatments. Resource-poor countries cannot afford to develop the public health interventions needed to control neglected diseases. In addition, neglected diseases do not represent an attractive market ...
متن کاملStepwise innovation adoption: a neglected concept in innovation research
Most innovation researchers tend to consider innovation adoption as a binary process, implying that companies have either adopted an innovation or not. In this paper we focus on e-commerce as an innovation that can be adopted stepwise. We distinguish between two levels of e-commerce, basic and advanced. Following Rogers’ (1995) innovation adoption model, we investigate the differences between c...
متن کاملNeglected Tropical Diseases, Neglected Data Sources, and Neglected Issues
BACKGROUND Lymphatic filariasis (LF) is a so-called neglected tropical disease, currently overshadowed by higher-profile efforts to address malaria, tuberculosis, and HIV/AIDS. Despite recent successes in arresting transmission, some 40 million people who already have the disease have been largely neglected. This study aims to increase understanding of how this vulnerable, neglected group can b...
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ژورنال
عنوان ژورنال: BMJ
سال: 2018
ISSN: 0959-8138,1756-1833
DOI: 10.1136/bmj.k1182